Institute for Molecular and Cellular Biology
HOMEResearch DivisionsResearch Outline

Section of Cell Structure and Function Division of Cellular Biology (Prof. Hanaoka)

Publications

  1. Matsumoto, K., Okuwaki, M., Kawase, H., Handa, H., Hanaoka, F., and Nagata, K. (1995). Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure. J. Biol.Chem. 270, 9645-9650.

  2. Sauer, F., Fondell, J. D., Ohkuma, Y., Roeder, R. G., and Jackle, H. (1995). Control of transcription by Krupel through interactions with TFIIB and TFIIEβ. Nature 375, 162-164.

  3. Ohkuma, Y., Hashimoto, S., Wang, C. K., Horikoshi, M., and Roeder, R. G. (1995). Analysis of the role of TFIIE in basal transcription and TFIIH-mediated CTD-phosphorylation through structure-function studies of TFIIE-α. Mol. Cell. Biol. 15, 4856-4866.

  4. van der Spek, P. J., Visser, C. E., Hanaoka, F., Smit, B., Hagemeijer, A., Bootsma, D., and Hoeijmakers, J. H. J. (1996). Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23. Genomics 31, 20-27.

  5. van der Spek, P. J., Eker, A., Rademakers, S., Visser, C., Sugasawa, K., Masutani, C., Hanaoka, F., Bootsma, D., and Hoeijmakers, J. H. J. (1996). XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes. Nucl. Acids Res. 24, 2551-2559.

  6. Sugasawa, K., Masutani, C., Uchida, A., Maekawa, T., van der Spek, P. J., Bootsma, D., Hoeijmakers, J. H. J., and Hanaoka, F. (1996). HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro. Mol. Cell. Biol. 16, 4852-4861.

  7. Ito, K., Asano, M., Hughes, P., Kohzaki, H., Masutani, C., Hanaoka, F., Curran, T., and Ito, Y. (1996). c-Jun stimulates origin-dependent DNA unwinding by polyomavirus large T antigen. EMBO J. 15, 5636-5646.

  8. Kawakami, K., Masuda, K., Nagano, K., Ohkuma, Y., and Roeder, R. G. (1996). Characterization of the core promoter of the Na, K-ATPase a1 subunit gene: Elements required for transcription by RNA polymerase II and III in vitro. Eur. J. Biochem. 237, 440-446.

  9. Mizuno, T., Okamoto, T., Yokoi, M., Izumi, M., Kobayashi, A., Hachiya, T., Tamai, K., Inoue, T., and Hanaoka, F. (1996). Identification of the nuclear localization signal of mouse DNA primase: nuclear transport of p46 subunit is facilitated by interaction with p54 subunit. J. Cell Sci. 109,2627-2636.

  10. Osada, H., Cui, C.-B., Onose, R., and Hanaoka, F. (1997). Screening of cell cycle inhibitors from microbial metabolites by a bioassay using a mouse cdc2 mutant cell line, tsFT210. Bioorg. Med. Chem. 5, 193-203.

  11. Ikehata, H., Kaneda, S., Yamao, F., Seno, T., Ono, T., and Hanaoka, F. (1997). Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mousemutant cells expressing a temperature-sensitive ubiquitin-activating enzyme E1. Mol. Cell. Biol. 17, 1484-1489.

  12. Ohkuma, Y. (1997). Multiple functions of general transcription factors TFIIE and TFIIH in transcription: Possible points of regulation by trans-acting factors. J. Biochem. 122, 481-489.

  13. Masutani, C., Araki, M., Sugasawa, K., van der Spek, P. J., Yamada, A., Uchida, A., Maekawa, T., Bootsma, D., Hoeijmakers, J. H. J., and Hanaoka, F. (1997). Identification and characterization of XPC-binding domain of hHR23B. Mol. Cell. Biol. 17, 6915-6923.

  14. Sugasawa, K., Ng, J. M. Y., Masutani, C., Maekawa, T., Uchida, A., van der Spek, P. J., Eker, A. P. M., Rademakers, S., Visser, C., Aboussekhra, A.,Wood, R. D., Hanaoka, F., Bootsma, D., and Hoeijmakers, J. H. J. (1997). Two human homologues of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity. Mol. Cell. Biol. 17, 6924-6931.

  15. Yokoi, M., Ito, M., Izumi, M., Miyazawa, H., Nakai, H., and Hanaoka, F. (1997). Molecular cloning of the cDNA for the catalytic subunit of plant DNA polymerase α and its cell-cycle dependent expression. Genes to Cells 2, 695-709.

  16. Sakamoto, A., Ono, K., Abe, M., Jasmin, G., Eki, T., Murakami, Y., Masaki,T., Toyo-oka, T., and Hanaoka, F. (1997). Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, δ-sarcoglycan, in hamster: An animal model of disrupted dystrophin-associated glycoprotein complex. Proc. Natl. Acad. Sci. USA 94, 13873-13878.

  17. Eki, T., Okumura, K., Abe, M., Kagotani, K., Taguchi, H., Murakami, Y., Pan, Z.-Q., and Hanaoka, F. (1998). Mapping of the human genes encoding cyclin H (CCNH) and the CDK-activating kinase (CAK) assembly factor MAT1 (MNAT1) to chromosome bands 5q13.3-q14 and 14q23, respectively. Genomics 47, 115-120.

  18. Mizuno, T., Ito, N., Yokoi, M., Kobayashi, A., Tamai, K., Miyazawa, H., and Hanaoka, F. (1998). The second largest subunit of the mouse DNA polymerase α-primase complex facilitates both the production and nuclear translocation of the catalytic subunit of DNA polymerase α. Mol. Cell. Biol. 18, 3552-3562.

  19. Okamoto, T., Yamamoto, S., Watanabe, Y., Ohta, T., Hanaoka, F., Roeder, R. G., and Ohkuma, Y. (1998). Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEβ subunit. J. Biol. Chem. 273, 19866-19876.

  20. Sugasawa, K., Ng, J. M. Y., Masutani, C., Iwai, S., van der Spek, P., Eker, A. P. M., Hanaoka, F., Bootsma, D., and Hoeijmakers, J. H. J. (1998). Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol. Cell 2, 223-232.

  21. Masutani, C., Araki, M., Yamada, A., Kusumoto, R., Nogimori, T., Maekawa, T., Iwai, S., and Hanaoka, F. (1999). XP-V correcting protein from Hela cells has a thymine dimer bypass DNA polymerase activity. EMBO. J. in press.

  22. Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S.,Takio, K.,and Hanaoka, F.(1999) The XPV gene codes for human DNA polymeraseÞ. Nature in press


HOMEResearch DivisionsResearch Outline

(C) 2002 Osaka University Institute for Molecular and Cellular Biology